Flavia  Müller

Flavia Müller

Doctoral Ph.D. Student

Phone: +41 44 63 58765

Address: Winterthurerstrasse 260, 8057 Zürich

Room number: TFA 00.28

flavia.mueller@vetpharm.uzh.ch

Curriculum Vitae

Name

Flavia Müller

Born 25th June, 1991 in Sursee, Switzerland
Nationality Swiss
Address

Institute of Veterinary Pharmacology and Toxicology, University of Zurich, Winterthurerstrasse 260, CH-8057 Zürich

Education and Academic Positions

02/2017 – pres.

Doctoral Studies (Ph.D.)

Pharmacology and Toxicology Group

Vetsuisse Faculty, University Zurich
09/2014 – 08/2016

Studies of Health Sciences and Technology (M.Sc.)

Major in Human Health and Nutrition

ETH Zurich, Switzerland
03/2016 – 08/2016

Master Thesis

“Impaired Nutritional Status in Geriatric Trauma Patients”

University Hospital Zurich, Switzerland
02/2015 – 12/2015

Research Assistant

Laboratory of Physiology and Behaviour, ETH Zurich, Switzerland
09/2011 – 08/2014

Studies of Health Sciences and Technology (B.Sc.)

ETH Zurich, Switzerland

Research Interests

Flavia Müller’s main research interests are centered upon the question of how early-life environmental adversities such as prenatal infection can influence brain development and shape the risk of long-term brain abnormalities, particularly with respect to the underlying epigenetic mechanism. Epigenetics refers to heritable changes in gene expression that does not involve changes in the base DNA sequence, and such epigenetic modifications may be efficient in transferring the negative effects of prenatal immune activation to the offspring. More specifically, she tests her hypothesis using a well-established translational mouse model of prenatal immune activation, which is based on administration of the viral mimic poly(I:C) during pregnancy, an established environmental risk factor of schizophrenia and autism. Flavia Müller combines differing methods such as behavioural testing, immunohistochemistry assays and various molecular techniques to assess epigenetic dysregulation and the therapeutic potential of epigenetically active drugs in maternal immune activated offspring.

Publications

Researcher-ID: C-4595-2018

 

FS Mueller, Polesel M, Richetto J, Meyer U and Weber-Stadlbauer U. (2018) Mouse models of maternal immune activation: Mind your caging system! Brain, Behavior, and Immunity; doi: 10.1016/j.bbi.2018.07.014

 

MA Labouesse, Polesel M, Clementi E, Müller F, Markkanen E, Mouttet F, Cattaneo A, and Richetto J. (2018) MicroRNA expression profiling in the prefrontal cortex: Putative mechanisms for the cognitive effects of adolescent high fat feeding. Scientific Reports; 8: 8344

 

FS Müller et al. (2017) Impaired nutritional status in geriatric trauma patients. European Journal of Clinical Nutrition; 71 (5): 602-606